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Genetic mutations can cause cancer…

A gene mutation is a permanent alteration in the DNA sequence that makes up the gene. The altered DNA sequence differs from the DNA sequence found in most people. Gene mutations are of kind kinds: Germline or hereditary mutations and acquired mutations.

Germline or hereditary mutations in BRCA1 and BRCA2 genes increase the risk of developing some cancers. Women are at risk for breast or ovarian cancers and men are at risk for prostrate or breast cancers. Also, among both genders there is an increased risk of pancreatic cancer and skin cancer.

If you have a family history of cancer…

Everyone above the age of 40 years should undergo annual screening for cancer. However, if you have a family history of breast or ovarian cancer, you can consider a germline genetic test (on a blood or saliva sample) to see if you are carrying a gene mutation that increases the risk. Family history would mean incidence of breast or ovarian cancer at a young age in two or more close relatives, such as parents or siblings or children. 

If you wish to consider genomic assessment, please approach the lab concerned directly or through a hospital. A special kit is sent to you, through which you need to courier a blood sample back to them. The sample is analysed by gene-mapping equipment and a personalised report is mailed back to you. Should the test detect an inherited mutation, you can take steps to lower the cancer risk.

Ahmedabad

FRIGE's Institute of Human Genetics

FRIGE House, Jodhpur Village Road, Satellite, Ahmedabad 380015

079-2692 1414 / 1415

geneticcentre.org

Bangalore

InterpretOmics India Pvt Ltd

329, 7th main, HAL 2nd Stage, Indira Nagar, Bangalore 560008

080-2521 2202

www.interpretomics.co

Bangalore

MedGenome Labs Pvt. Ltd.

3rd Floor, Narayana Netralaya Building, Narayana Health City, # 258/A, Bommasandra, Hosur Road, Bangalore 560099

080-6715 4900, 6715 4901

diagnostics.medgenome.com

Bangalore

Strand Life Sciences Pvt. Ltd.

5th Floor, Kirloskar Business Park, Bellary Road, Hebbal, Bangalore 560024

080-4078 7263, 4078 7299

strandls.com

Bangalore Delhi Hyderabad Kolkata Mumbai

Positive Bioscience Ltd

1800-3070-6727

positivebioscience.com

Chennai

Xcode Life Sciences Pvt. Ltd.

6B, Eldorado, 112, Nungambakkam High Road, Nungambakkam, Chennai 600034

044-4319 2999

www.xcode.in

Delhi-NCR

igenomix

L-7, First Floor, Green park Extension, Near SBI, New Delhi 110016

011-6651 7800

www.igenomix.co.in

Hyderabad

Lords Mark Microbiotech

502, Sonthalia Emerald, Raj Bhavan Road, Somajiguda, Hyderabad 500082

040-4958 3100, 80197 15028

mydna.lordsmicrobiotech.com

Hyderabad

BioAxis DNA Research Centre Private Limited

13-51, Sri Lakshmi Nagar Colony, GSI Post BandalGuda (L B Nagar), Hyderabad 68

040-24034503, 092463 38983

www.dnares.in

Hyderabad

DNA Labs India

H.No: 3-4-871, GHMC No: 571, Barkatpura-Street 11, Hyderabad 500027

040-4964 4991

www.dnalabsindia.com

Hyderabad

Mapmygenome

Royal Demure, HUDA Techno Enclave, Plot 12/2, Sector 1, Madhapur, Hyderabad 81

1800-102- 4595

www.mapmygenome.in

Mumbai

Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), R&D arm of the Tata Memorial Hospital

Kharghar, Navi Mumbai 410210

022-2740 5000

www.actrec.gov.in

Mumbai

Personal genomics Clinic, Kokilaben Dhirubhai Ambani Hospital

Raosaheb Achutrao Patwardhan Marg, Four Bungalows, Andheri (W), Mumbai 53

022-3099 9999, 3069 6969

Web Page

Nashik

Datar Genetics Limited

F8, D-Road, Ambad, Nashik 422010

1800-121-0700, Whatsapp: 75077 78182

datarpgx.org

Pune

GenePath Diagnostics

1260/B Jangli Maharaj Road, Shivajinagar (Deccan Gymkhana), Pune 411004

020-2553 4780, 4856 6661, 96234 95511

www.genepathdx.com